Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1978-07-07
1980-11-04
Coughlan, Jr., Paul M.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
424180, 536 54, 544325, 542425, A61K 31505, C07D23949
Patent
active
042320232
ABSTRACT:
The novel derivatives correspond to the general formula II: ##STR1## in which: R.sub.1 R.sub.2 R.sub.3 and R.sub.4 represent identical or different groups which can each be a hydrogen or halogen atom or an alkyl group, alkoxy, or benzyloxy group and R is the residue of an R--CHO aldehyde selected from among linear or branched saturated aliphatic aldehydes including 1 to 4 carbon atoms or again represents the Z--CH.dbd.CH radical in which Z represents a hydrogen atom, a linear or branched saturated alkyl group, an aromatic nucleus or an aromatic heterocyclic nucleus or again R represents the radical HO CH.sub.2 (CH OH)n--in which n has the value of 3 or 4. The novel compounds have high solubility in water and antibacterial activity and potentiating power.
REFERENCES:
patent: 3111521 (1963-11-01), Hoefle et al.
Stogryn, J. Medicinal Chem., 1973, vol. 16, No. 12, pp. 1399-1401.
Dick Pierre R.
Rombi Max
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