Novel resolution method of racemic mixture

Details Novel resolution method of racemic mixture Novel resolution method of racemic mixture

1984-10-23

1987-04-07

Brust, Joseph Paul

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitriles

558451, 560106, 260503, 562443, 562582, 562585, C07C12143

Patent

active

046563032

ABSTRACT:
A novel resolution method of a racemic mixture, wherein four kinds of salts are dissolved in a resolving solvent to fractionally crystallize a desired optically active isomer through an exchange reaction between counter ions.

REFERENCES:
patent: 3167566 (1965-01-01), Overby
Strack, et al., "Hoppe Seyler's Zeitschrift fur Physiologische Chemie", Band 318, (1960), Summary, p. 137.
Organic Syntheses, vol. 5, 1973, John Wiley and Sons, pp. 932-936.
Journal of the Pharmaceutical Society of Japan, vol. 81, No. 5 (1961), pp. 778, 779 and 780.

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