Novel receptors for efficient determination of ligands and their

Chemistry: analytical and immunological testing – Biospecific ligand binding assay

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435 7, 436 63, 436503, 436537, 530402, 530806, 530808, 935 81, 935109, G01N 33566, G01N 33542

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active

048596094

ABSTRACT:
Hybrid receptors are provided that comprise (a) the ligand binding domain of a predetermined receptor and (b) a heterologous reporter polypeptide. The hybrid receptors are useful for convenient and large scale assay of biologically active ligands or their antagonists or agonists.

REFERENCES:
patent: 3935074 (1976-01-01), Rubenstein et al.
patent: 4363758 (1982-12-01), Masuko et al.
patent: 4374925 (1983-02-01), Litman et al.
patent: 4504587 (1985-03-01), Timpl et al.
patent: 4544629 (1985-10-01), Rice et al.
patent: 4595655 (1986-06-01), Self
Cobb et al., Biochem. Biophys. Acta, 738: 1-8 (1984).
Siegel et al., J. Biol. Chem., 256(17): 9266-9273 (1981).
Emr et al., J. Cell Biol., 86: 701-711 (1980).
Coulton et al., J. Bacteriol. 165(1):181-192 (1986).
Steiner et al., Methods in Enzymology, 109: 346-350 (1985).
Prywes R. et al., "EMBO Journal", 5(9): 2179-2190 (Sep. 1986).
Riedel, H. et al., "Science", 236: 197-200 (Apr. 1987).
Riedel, H. et al., "Nature", 324(6092): 68-70 (Nov. 1986).
Kris, R. M. et al., "Cell", 40: 619-625 (Mar. 1985).
Livneh, E. et al., "J. Biol. Chem.", 261(27): 12490-12497 (Sep. 1986).
Ullrich, A. et al., "Leukemia: Recent Advances in Biology and Treatment", Alan R. Liss, Inc., pp. 277-292 (1985).
Ullrich, A. et al., "Cancer Cells 3/Growth Factors & Transformation", Cold Springs Harbor Laboratory (Jun. 1985), pp. 1-9.
Hunter T., "Nature", 313: 740-741 (Feb. 1985).
Ullrich, A. et al., "Nature", 313: 756-761 (Feb. 1985).
King, G. et al., "J. Biol. Chem.", 267(14): 10869-10873 (1982).

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