Novel radioactive estradienes labelled with iodine

Details Novel radioactive estradienes labelled with iodine Novel radioactive estradienes labelled with iodine

1984-06-14

1987-01-27

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424 11, 514182, C07J 100

Patent

active

046393366

ABSTRACT:
Novel radioactive estradienes labelled with iodine of the formula ##STR1## in the form of their syn or anti isomers or mixtures thereof wherein the wavy line indicates anti or syn position, R is selected from the group consisting of hydrogen, alkyl of 1 to 6 carbon atoms and acyl of an organic carboxylic acid of 1 to 12 carbon atoms and R.sub.1 is the residue of an amino acid R.sub.1 NH.sub.2 possessing an iodine acceptor group or a derivative thereof labelled with iodine .sup.125 or .sup.131 and their preparation and novel intermediates, antigens prepared from the compounds of formula I and bovine seric albumin or human seric albumin and their preparation and their use for the preparation of antibodies.

REFERENCES:
"Steroids"-vol. 32, No. 4 (1978), pp. 467-486, an article by Allen et al.

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