Novel pyrido[2,3-f](1,4)thiazepines and pyrido[3,2-b](1,5)benzot

Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...

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540548, 540552, C07D28118, C07D28110, C07D28112

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active

050754408

ABSTRACT:
Novel pyrido[2,3-f] [1,4]thiazepines and novel pyrido[3,2-b] [1,5]benzothiazepines of the formula: ##STR1## These compounds are useful as calcium channel antagonists with cardiovascular, antiasthmatic and antibronchoconstriction activity. Also described are methods of producing the novel compounds and intermediates thereof.

REFERENCES:
patent: 4285955 (1981-08-01), Wehinger et al.
patent: 4532248 (1985-07-01), Franckowiak et al.
Federsel et al., Tetrahedron Letters, vol. 21, 1980, pp. 2429-2432.
Pagani, J. Chem. Soc. Pepkins Trans. 11, 1974, pp. 1392-1397.

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