Novel pyridine 1-oxides

Details Novel pyridine 1-oxides Novel pyridine 1-oxides

1975-06-20

1978-01-10

Jiles, Henry R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260268H, 260296R, 424246, 42424856, 424250, 424263, 4242484, 424267, 2602433, 544 60, 544 82, 544124, C07D40104

Patent

active

040678741

ABSTRACT:
Some new 4-amino-2-lower-alkyl-6-variable-pyridine-1-oxides are described. A new process is provided. The 6-variable is lower-alkyl, amino or substituted amino including saturated heterocyclic amino, e.g., pyrrolidinyl, piperidino, etc. The compounds are hypotensive agents and reduce blood pressure in animals.

REFERENCES:
ochial, "J. Org. Chem.", 18 pages, 534-551 (1953).
Culvenor, "Amine Oxides", Rev. Pure and Applied Chem. vol. 3, pp. 83-114 (1953).
Anker et al., "J. Chem. Soc.", (1946) pp. 117-120.

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