Novel pyrazinoxide compound of NF-1616-904 and a pharmaceutical

Details Novel pyrazinoxide compound of NF-1616-904 and a pharmaceutical Novel pyrazinoxide compound of NF-1616-904 and a pharmaceutical

1990-05-07

1991-06-04

Shen, Cecilia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514825, 544405, A61K 31495, C07D40306

Patent

active

050214195

ABSTRACT:
A novel pyrazinoxide compound of NF-1616-904 having the formula (1), ##STR1## prepared by hydrolyzing the intermediate compound of NF-1616-902 which is separated from a culture broth of a microorganism belonging to the genus Thielavia.
The pyazinoxide compound of NF-1616-904 possess biological and pharmacological activities, and is useful agent for preventing and treating diseases caused by superoxide radicals (O.sub.2.sup.-), and nephritis.

REFERENCES:
Simpson et al., Journal of Laboratory and Clinical Medicine, pp. 13-30 (1987).
Laurent et al., American Journal of Physiology (1986) pp. 765-776.
Fantone et al., The American Journal of Pathology (1982) pp. 397-418 (vol. 107, No. 3).
Taber's Cyclopedic Medical Dictionary, Edited by Thomas 16 Edition, pp. 922-923, 1580-1581 (1989).
Tsuruo et al., CA 105-164596m (1986) "Characteristics of Vincristine Resistance in . . . ".
Chemical Abstracts, vol. 95, 1981, p. 738, Abstract No. 7743q.

Affiliated with

Also associated with

Rating

Novel pyrazinoxide compound of NF-1616-904 and a pharmaceutical does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Novel pyrazinoxide compound of NF-1616-904 and a pharmaceutical , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel pyrazinoxide compound of NF-1616-904 and a pharmaceutical will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1026531