Novel prostaglandin precursors in polymeric form

Details Novel prostaglandin precursors in polymeric form Novel prostaglandin precursors in polymeric form

1977-08-10

1980-07-08

Marquis, Melvyn I.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 49, 536 51, 536107, 536108, 536110, 536112, C08B 3102

Patent

active

042118654

ABSTRACT:
A novel polymer consisting of a macromolecular polysaccharide matrix which is esterified in whole or in part by activated polyunsaturated acids containing twenty carbon atoms. Typical of these acids are, for example, 8, 11, 14-eicosatrienoic acid, 5, 8, 11, 14-eicosatetraenoic acid and 5, 8, 11, 14, 17-eicosapentenoic acid. These polymers are therapeutically useful products which have utility in the same fields of application as the prostaglandins but absent their adverse side effects.

REFERENCES:
patent: Re28809 (1976-05-01), Tessler
patent: 2954372 (1960-09-01), Novak
patent: 3720663 (1973-03-01), Tessler
patent: 4069387 (1978-01-01), Hayashi et al.
Condensed Chemical Dictionary, p. 349, 1956.
Whistler et al., Starch: Chemistry and Technology, 1965, pp. 358 and 376.

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