Novel process for the synthesis of quinoxaline and benzimidazole

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

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544353, 544354, 548323, C07B 4300, C07D24152, C07D23508, C07D23518

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048661759

ABSTRACT:
The synthesis of quinoxaline and benzimidazole-N-oxides and of ester amd amide derivatives of 3-hydroxy-2-quinoxalinecarboxylic acid by a movel process consisting of the reaction between a benzofuroxan and an activated methylene-containing compound under basic conditions.

REFERENCES:
patent: 3398141 (1968-08-01), Haddadin
patent: 3660398 (1972-05-01), Ley et al.
Fieser et al., "Organic Chemistry", pp. 224-228.
Issidorides et al., J. Org. Chem 31, 4067-8, (1966).
Boulton et al., Chem. Comm. 1966, 741-2.

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