Novel process for the preparation of 1-N-(alpha-substituted-omeg

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 10, 536 12, C07H 1520

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active

041257065

ABSTRACT:
A 1-N-(.alpha.-substituted-.omega.-aminoacyl)-3'-deoxyribostamycin, which is a useful antibiotic active against various drug-resistant bacteria, can be prepared advantageously by a process starting from a protected derivative of ribostamycin in the form of 1,6-carbamate and comprising the 3'-deoxygenation, the splitting of the carbamate linkage and the 1-acylation.

REFERENCES:
patent: 3929762 (1975-12-01), Umezawa et al.
patent: 3960833 (1976-06-01), Naito et al.
patent: 4003922 (1977-01-01), Kavadias et al.

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