Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.
Patent
1987-12-22
1990-12-25
Moskowitz, Margaret
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Lymphokines, e.g., interferons, interlukins, etc.
424 855, C07K 1300, C07K 1526, A61K 3766
Patent
active
049804553
ABSTRACT:
The present invention provides a novel polypeptide which shows higher IFN-.gamma. activity than intact IFN-.gamma. and a method of producing the same.
The polypeptides not only possess a remarkable antiviral activity, antitumor activity, immunopotentiating activity but also is highly stable, therefore, it can be used advantageously as pharmaceuticals.
REFERENCES:
patent: 4832957 (1989-05-01), Engels et al.
Honda Susumu
Nishimura Osamu
Sakaguchi Masao
Baker R. Keith
Conlin David G.
Eisenstein Ronald I.
Moskowitz Margaret
Takeda Chemical Industries Ltd.
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