Drug – bio-affecting and body treating compositions – Lymphokine – Interferon
Patent
1987-12-16
1989-11-21
Rosenberg, Peter D.
Drug, bio-affecting and body treating compositions
Lymphokine
Interferon
435 91, A61K 3900, A61K 4502
Patent
active
048821470
ABSTRACT:
Polyribonucleotide analogs which are partially substituted by the introduction of mercapto groups and fluorine at the 5-position of some of their cytosine and uracil bases possess effective in vivo antitumor activity. Double stranded complexes formed from such polynucleotides are especially active as interferon inducers.
REFERENCES:
patent: 3594278 (1971-07-01), Naylor
patent: 3850749 (1974-11-01), Kaufmann
O'Mally, J. A., et al, Molecular Pharmacology, 11, 61-69 (1975).
Vastola, K. A. et al, Research Communications in Chemical Pathology & Pharmacology, vol. 45, No. 3, 407-419 (1984).
Alderfer, J. L. et al, Polymeric Materials in Medication, Gebelein, C. G. et al, Editors, Plenum, New York, 125-138 (1985).
Bardos Thomas J.
Ho Yau-Kwan
Hughes, Jr. Robert G.
Kasper Steven J.
Dunn Michael L.
Ellis Howard M.
Rosenberg Peter D.
The Research Foundation of State University of New York
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