Novel platinum complex, antineoplastic agent containing the same

Details Novel platinum complex, antineoplastic agent containing the same Novel platinum complex, antineoplastic agent containing the same

1988-11-23

1990-07-03

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548402, C07F 1500, A61K 31555

Patent

active

049392565

ABSTRACT:
Novel platinum complex of the formula: ##STR1## wherein n is an integer of 1 or 2 and A is a ligand of the formula: ##STR2## which has excellent antineoplastic activity and is useful as an antineoplastic agent for the treatment of various malignant tumors, and a pharmaceutical composition containing the platinum complex as an active ingredient, and an intermediate for preparing the compound.

REFERENCES:
patent: 4575550 (1986-03-01), Totani
Dr. Nicolaos E. Madias, "Platinum Nephrotoxicity", The American Journal of Medicine, vol. 65, Aug. 1978, pp. 307-314.

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