Novel platinum complex

Details Novel platinum complex Novel platinum complex

1989-12-18

1991-04-16

Prescott, Arthur C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heavy metal containing

556 40, C07F 968

Patent

active

050084194

ABSTRACT:
A platinum complex having the following formula (I) is disclosed, ##STR1## wherein R.sup.1 and R.sup.2 may be the same or different and each independently represents a methyl group or an ethyl group, and the configuration of 1,2-diaminocyclohexane is either cis-, trans-l-, trans-d-, or trans-dl-.
The compound possess excellent antitumor activity with a high therapeutic index and abundant water solubility, and thus are effective as an antitumor agent.

REFERENCES:
patent: 4169846 (1979-10-01), Kidani et al.
patent: 4861905 (1989-08-01), Nowatari et al.

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