Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1987-12-03
1989-08-15
Lee, Lester L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530330, A61K 3720, C07K 510
Patent
active
048575089
ABSTRACT:
Novel tetrapeptide derivatives are provided which have useful activity as inhibitors of platelet aggregation. These compounds have the sequence X-Gly-Asp-Y wherein X is illustrated by arginine and Y is illustrated by O-methyltyrosine amide.
REFERENCES:
patent: 3795667 (1974-03-01), Ondetti
patent: 4517686 (1985-05-01), Ruoslahti et al.
patent: 4578079 (1986-03-01), Ruoslahti et al.
patent: 4589881 (1986-05-01), Pierschbacher et al.
patent: 4590003 (1986-05-01), Twardzik
patent: 4596790 (1986-06-01), Trygstad et al.
patent: 4614517 (1986-09-01), Ruoslahti et al.
patent: 4661111 (1987-04-01), Ruoslahti et al.
patent: 4683291 (1987-07-01), Zimmerman et al.
Kloczewiak et al., Biochem. 23, 1767-1774 (1984).
Plow et al., Proc. Natl. Acad. Sci. 82, 8057-8061 (1985).
Ruggeri et al., Ibid. 83, 5708-5712 (1986).
Ginsberg et al., J. Biol. Chem. 260(7), 3931-3936 (1985).
Haverstick et al., Blood 66(4) 946-952 (1985).
Adams Steven P.
Feigen Larry P.
Miyano Masateru
G. D. Searle & Co.
Lee Lester L.
Meyer Scott J.
Monsanto Company
Williams, Jr. James W.
LandOfFree
Novel platelet-aggregation inhibitor peptide derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Novel platelet-aggregation inhibitor peptide derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel platelet-aggregation inhibitor peptide derivatives will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-121698