Novel physiologic chemical method of labeling protein substances

Details Novel physiologic chemical method of labeling protein substances Novel physiologic chemical method of labeling protein substances

1984-04-23

1987-01-13

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

424 9, 534 10, 556 1, 556 28, 556 81, A61K 4300, A61K 4900

Patent

active

046363807

ABSTRACT:
A novel chemical method of labeling plasma proteins, compounds and substances containing proteins with the radionuclides of indium at physiologic pH 6-8 condition producing an efficiently labeled radioactive tracer material suitable for biomedical applications. These radiolabeled protein substances are not denatured by the labeling process but retain their native physiobiological properties. This novel labeling technique provides a simple and rapid means of labeling plasma proteins such as human serum albumin, transferrin, lactoferrin, fibrinogen, and immunoglobulin or antibodies with .sup.111 In or .sup.113m In for scintigraphic imaging which may allow visualization of thrombi, emboli, myocardial infarcts, infectious lesions, tumors or any vascular abnormalities in the body.

REFERENCES:
patent: 4335095 (1982-06-01), Kelly
patent: 4485086 (1984-11-01), Wong
patent: 4497791 (1985-02-01), Gamble et al.

Affiliated with

Also associated with

Rating

Novel physiologic chemical method of labeling protein substances does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Novel physiologic chemical method of labeling protein substances, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel physiologic chemical method of labeling protein substances will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2354909