Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ketone doai
Patent
1990-03-02
1992-03-03
Moezie, F. T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ketone doai
514685, 514686, 514781, 424488, 424489, A61K 3112
Patent
active
050933728
ABSTRACT:
A pharmaceutical composition which is a physical mixture of exifone and certain water soluble cellulose derivatives. The mixture exhibits surprisingly improved solubility and bio availability.
REFERENCES:
patent: 4015017 (1977-03-01), Gazave et al.
patent: 4145440 (1979-03-01), Fitch et al.
patent: 4412986 (1983-11-01), Kawata et al.
CA 89(22): 186079y, "Drugs contg. 2,3,4,3',4", 5" Hexahydroxybenzophenone"1978, Laboratories Pharmascience.
CA 107(13):109260p, "The Effects of Cxifone, New Agent for Senile Memory Disorder," Porsolt et al., 1987.
Sugimoto et al., "Dissolution & Absorption of Nifedipine from Nifedipine-PVP Copreaprtate", Drug Development & Ind. Pharmacy 6(2) 137-160 (1980).
Mizobe et al., "Application of Solid Dispersion to Enhance Dissolution Rate & Bioavailability of Bisbentiamine in Enteric Tablets", vol. 43, #1 (1983).
Nakahasi Nobumitsu
Shimojo Fumio
Toyoshima Kenzo
Uedo Yoshio
Yasumara Mitsuru
Bierman Jordan B.
Fujisawa Pharmaceutical Co. Inc.
Moezie F. T.
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