Novel penicillins and their preparation

Details Novel penicillins and their preparation Novel penicillins and their preparation

1975-09-03

1977-01-18

Schwartz, Gerald A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424271, C07D49968

Patent

active

040038874

ABSTRACT:
Novel penicillins of the formula: ##STR1## wherein the ring A is a benzene ring or a 5 or 6-membered heteroaromatic ring containing one or two nitrogen atoms as the hetero atom, on which one or more of lower alkyl, lower alkoxy, lower alkylthio, lower haloalkyl, lower alkylenedioxy halogen, hydroxyl, nitro, free or protected amino, lower alkylamino, di(lower)alkylamino and lower alkanoylamino may be present, Z is a nitrogen atom or a methylene group, X is an oxygen atom or a sulfur atom, Y is a hydrogen atom, a lower alkoxycarbonyl group or a lower alkanoyl group, R.sub.1 is a free or protected hydroxyl group and R.sub.2 and R.sub.3 are each a hydrogen atom or a halogen atom, and their non-toxic pharmaceutically acceptable salts, and their preparation.

REFERENCES:
patent: 3192198 (1965-06-01), Naylor et al.
patent: 3433784 (1969-03-01), Long et al.
patent: 3579501 (1971-05-01), McGregor
patent: 3835115 (1974-09-01), Richardson
patent: 3864329 (1975-02-01), Tobiki et al.
patent: 3870708 (1975-03-01), Gruszecki et al.

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