Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1985-09-27
1987-11-10
Jiles, Henry R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514318, 514341, 546193, 546194, 546277, 546256, 546270, 546271, 546273, 546276, 546278, 546279, 544360, 544295, 544333, 540481, 548131, 548128, A61K 3141, C07D40104, C07D40106, C07D41304
Patent
active
047057866
ABSTRACT:
A compound of the formula ##STR1## wherein T.sub.1 is lower alkylene, lower alkenylene or a single bond; X is ##STR2## T.sub.2 is carbonyl, lower alkylene or a single bond; R.sub.2 is phenyl, phenoxy, pyridyl, pyrimidinyl, furyl, thienyl, lower cycloalkyl or adamantyl;
REFERENCES:
patent: 4414213 (1983-11-01), Poindexter et al.
patent: 4532248 (1985-07-01), Franckowiak et al.
Opie, L. H., Calcium Antagonists and Cardiovascular Disease, vol. 9, (1984), pp. 165-173.
Bossert et al., 4-Aryldihydropyridines, Angew. Chem. Int. Ed. Engl. 20, 762-769 (1981).
Schramm et al., Novel Dihydropyridines, Nature, vol. 303 (1983), Jun., 535-537.
Goodman et al., The Pharmacological Basis of Therapeutics, p. 28.
Hara Youichi
Miyagishi Akira
Ozato Yukinori
Tamura Nobuhiko
Yamamoto Michihiro
Jiles Henry R.
Richter J.
Sumitomo Pharmaceuticals Company Limited
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