Novel orthoester polymers and orthocarbonate polymers

Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – From phenol – phenol ether – or inorganic phenolate

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424 19, 424 20, 528219, 528249, 528392, 528405, 528425, C08G 6528, C08G 6534

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active

041806468

ABSTRACT:
The invention concerns orthoester and orthocarbonate polymers having a repeating mer comprising a hydrocarbon radical and a symmetrical dioxycarbon unit of the general formula: ##STR1## wherein R.sub.1 is a multivalent hydrocarbon radical, R.sub.2 and R.sub.3 are hydrocarbon radicals with at least one of R.sub.2 or R.sub.3 bonded to the dioxycarbon through an oxygen linkage, and which polymers are synthesized by reacting a polyol with an orthoester or orthocarbonate. The polymers are useful for making articles of manufacture, including devices and coatings for delivering beneficial agents.

REFERENCES:
Mohrotra et al., Indian Journal Applied Chemistry, vol. 28-No. 2, (1965) Reactions of Ethyl Orthoformate with Glycols, pp. 53-58.
Crank, Aust. Journal Chemistry, "Derivatives of Orthoacids", vol. 17, (1964), pp. 1392-1398.
DeWolfe, Carboxylic Ortho Acid Derivatives, (1970) Academic Press Inc., New York, pp. 7-9 & 21-22.
Bailey, et al., Polymer Preprint. American Soc. Division Polymer Chem., vol. 13, No. 1, (1972), "The Polymerization of a Spiroortho Ester", pp. 281-286.

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