Novel N.sup.4 -Acyloxy-2,2'-cyclocytidines and process for prepa

Details Novel N.sup.4 -Acyloxy-2,2'-cyclocytidines and process for prepa Novel N.sup.4 -Acyloxy-2,2'-cyclocytidines and process for prepa

1977-08-26

1979-02-27

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, C07H 1700, A61K 3170

Patent

active

041420411

ABSTRACT:
N.sup.4 -Acyloxy-2,2'-cyclocytidines of the formula: ##STR1## and N.sup.4, 3',5'-tri-O-acyl-2,2'-cyclocytidines of the formula: ##STR2## wherein R' and R are the same and represent an acyl group; which are useful for decreasing the total packed cell volume ratio (T/C%) with respect to ascitic form of Sarcoma 180 in small animals, and thus prolonging their lives.

REFERENCES:
patent: 399104 (1976-11-01), Ishida et al.
patent: 3792040 (1974-02-01), Moffatt et al.
patent: 3920630 (1975-11-01), Wechter et al.

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