Chemical apparatus and process disinfecting – deodorizing – preser – Process disinfecting – preserving – deodorizing – or sterilizing – Using disinfecting or sterilizing substance
Patent
1989-02-27
1990-07-31
Warden, Robert J.
Chemical apparatus and process disinfecting, deodorizing, preser
Process disinfecting, preserving, deodorizing, or sterilizing
Using disinfecting or sterilizing substance
422 28, 424533, 435 2, 435288, 514833, 530385, A61L 218, C07K 1506
Patent
active
049449206
ABSTRACT:
It is well known that the transfusion of human blood and blood components carriers with it a substantial risk of transmission of AIDS and many other diseases. This disclosure describes a method of disinfecting red blood cells to make them safer for human transfusion, while maintaining their biologic activity. A sterilizing solution is prepared from, e.g., a commercially available disinfectant (LD.TM. Alcide Corporation) containing primarily lactic acid and sodium chlorite. Normal saline solution is used as diluent instead of distilled water. The red cells are exposed to the disinfectant for a time sufficient to inactivate or reduce the infectivity of disease agents. The normal-saline environment prevents or deters hemolysis. The blood cells are then washed with normal saline solution until the disinfectant concentration is insignificant. The blood is then safe for human transfusion.
REFERENCES:
patent: Re27359 (1972-05-01), Ilg
patent: Re31799 (1984-12-01), Alliger
patent: 1556120 (1925-10-01), Mills
patent: 2134679 (1928-11-01), Allen
patent: 2897123 (1959-07-01), Singher
patent: 3031378 (1962-04-01), Ishidate
patent: 3041242 (1962-06-01), Barr et al.
patent: 3100737 (1963-08-01), Auerswald et al.
patent: 4084747 (1978-04-01), Alliger
patent: 4314997 (1982-02-01), Shanbrom
patent: 4481189 (1984-11-01), Prince
patent: 4632980 (1986-12-01), Zee et al.
Alcide Corporation Product Literature on LD.TM. Disinfectant, (1985), 5 pages.
Gallo et al., Science, vol. 224, 4 May 1984, pp. 500-503.
Sarin et al., J. Clin. Immunology, vol. 4, No. 6, pp. 415-423.
Wong-Staal et al., Nature, vol. 317, 3 Oct. 1985, pp. 395-402.
Sarin et al., NE J. Medicine, Nov. 28, 1985, p. 1416.
Johnston Jill
University of Southern California
Warden Robert J.
LandOfFree
Novel method to treat blood does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Novel method to treat blood, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel method to treat blood will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1397898