Novel means and method for diagnostic quantitation of serum or p

Details Novel means and method for diagnostic quantitation of serum or p Novel means and method for diagnostic quantitation of serum or p

1976-09-17

1978-03-14

Marantz, Sidney

Chemistry: physical processes

Physical processes

Crystallization

23259, 206219, 252408, G01N 3316

Patent

active

040788920

ABSTRACT:
Method of determining total and direct bilirubin in blood serum or plasma. A first reagent containing sulfanilic and hydrochloric acids and a second reagent containing sulfanilic acid, hydrochloric acid and dimethyl sulfoxide are disposed in a scheme of reagent reservoirs. Into some of the reservoirs is also placed sodium nitrite contained in frangible capsules. The frangible capsules are broken with the resulting formation of a diazonium reagent. Blood serum or plasma, standard bilirubin solution and control serum are added to the reservoirs according to the analytical scheme. The subsequent color developments in the reservoirs are correlated to the bilirubin contents.

REFERENCES:
patent: 3068855 (1962-12-01), Furlong
patent: 3446596 (1969-05-01), Salivar
patent: 3449081 (1969-06-01), Hughes
patent: 3476515 (1969-11-01), Johnson
patent: 3511607 (1970-05-01), Green
patent: 3585004 (1971-06-01), Mast
patent: 3652222 (1972-03-01), Denney
patent: 3814586 (1974-06-01), Fraser
patent: 3825411 (1974-07-01), Morin
patent: 3986834 (1976-10-01), Steinbrink

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