Novel macrolide antibiotics and preparation thereof

Details Novel macrolide antibiotics and preparation thereof Novel macrolide antibiotics and preparation thereof

1979-05-10

1981-09-22

Castel, Benoit

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

Having a known elemental analysis

424122, 435 75, 435 76, 435169, 435867, C12P 1960, A61K 3574

Patent

active

042910218

ABSTRACT:
A novel microorganism species belonging to the genus Micromonospora, i.e. Micromonospora sp. A 11725 is found to be capable of producing novel macrolide antibiotics A 11725 I, A 11725 II and A 11725 III. Novel antibiotics A 11725 Ia and A 11725 IIa are also found to be derived by chemical modification of the antibiotics A 11725 I and A 11725 II, respectively. All of these antibiotics or salts thereof exhibit excellent antibacterial and anti-mycoplasmal activities against various microorganisms such as Staphylococcus or Mycoplasma, and therefore useful for various purposes including medicaments.

REFERENCES:
patent: 4032631 (1977-06-01), Celmer et al.
patent: 4162305 (1979-07-01), Nara et al.

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