Novel isoxazole and isoxazoline compounds with anticonvulsant ac

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514379, 514380, 548240, 548241, 548243, 548245, 548246, 548247, 548248, 548473, 560358, 564305, 568716, A61K 3142, C07D26004, C07D26110, C07D26120

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050596144

ABSTRACT:
The object of the invention are anticonvulsant heterocyclic compounds of general formula: ##STR1## in which R.sub.1 and R.sub.2 is each selected from C.sub.1 -C.sub.4 alkyl, phenyl, benzyl, trifluoromethyl or halogen, R.sub.3 is selected from hydrogen, hydroxy, C.sub.1 -C.sub.4 alkyl or alkoxy, R.sub.4, in position 3 or 5, is selected from hydrogen, trifluoromethyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkyl, or C.sub.1 -C.sub.4 hydroxyalkyl,

REFERENCES:
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patent: 4322429 (1982-03-01), Burow, Jr.
Paul et al., Bull. Chim. Soc. Fr., pp. 140-142 (1963).
Bianchi et al., Chemical Abstracts, vol. 70, No. 47343 (1969).
Ammermann et al., Chemical Abstracts, vol. 96, No. 20085 (1982).

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