Organic compounds -- part of the class 532-570 series – Organic compounds – Silicon containing
Patent
1978-07-03
1981-01-06
Shaver, Paul F.
Organic compounds -- part of the class 532-570 series
Organic compounds
Silicon containing
C07F 718
Patent
active
042436052
ABSTRACT:
Novel isocyanates such as, for example, blocked L-tyrosine methyl ester isocyanate, are reacted with compounds of biological, clinical interest or the like such as, for example, digoxin, to form derivatives receptive to tagging, as by radioliabeling. The tagged derivatives may then be employed to determine the presence of the compound of interest in nanomolar or even picomolar amounts by using clinical analysis techniques such as radioimmunoassay.
REFERENCES:
patent: 4031121 (1977-06-01), Gervase
Eisenhardt, Jr. William A.
Hedaya Eddie
Theodoropulos Spyros
Humphreys Harrie M.
Shaver Paul F.
Union Carbide Corporation
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