Novel intermediates and an improved process for producing the co

Details Novel intermediates and an improved process for producing the co Novel intermediates and an improved process for producing the co

1988-03-28

1990-02-13

Robinson, Douglas W.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26039745, 2603975, 514178, 514179, 514182, C07J 000, A61K 3156

Patent

active

049004778

ABSTRACT:
An improved process for the large scale production of the compound (3.beta.,5.alpha.)-3-hydroxycholest-8(14)-en-15-one is described and two new compounds which have utility as intermediates in synthetic routes to the subject compound are disclosed.

REFERENCES:
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Martin et al., Biochem. & Biophys. Res. Comm., 39, 1170-1174 (1980).
Kamono et al., Can. J. Chem., 51, 1973-1976 (1973).
Parish et al., Chem. & Phys. of Lipids, 18, 233-239 (1977).
Parish et al., J. Org. Chem., 45, 4034-4037 (1980).
Dolle et al., J. Org. Chem., 51, 4047-4053 (1986).

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