Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1980-08-13
1982-07-20
Ford, John M.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
260455R, 2604105, 560109, 560121, 560123, 560128, 560138, 564374, 564381, A61K 31265, C07C 6976, C07C 6974, C09F 508
Patent
active
043406033
ABSTRACT:
Novel, transient inotropic prodrug forms of the N-(2-phenylethyl)-.omega.-phenylalkylamines, notably of dobutamine, have (i) the structural formula (I): ##STR1## with the proviso that at least one R.sup.1, R.sup.2 or OR.sup.1, when R.sup.7 and/or R.sup.10 is OR.sup.1, must be R.sup.3 COXCH(R.sup.4)-- or R.sup.3 COXCH(R.sup.4)O--, respectively.
REFERENCES:
Chem. Abstracts, 85:424w, vol. 85, p. 419, 1976.
Burger, Medicinal Chemistry, Interscience Pub., Inc., NY, 1960, pp. 330-337 and 349-355.
Bodor Nicholas S.
Pogany Stefano A.
Sloan Kenneth B.
Ford John M.
Interx Research Corporation
Whittenbaugh Robert C.
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