Novel inhibitor peptides I

Details Novel inhibitor peptides I Novel inhibitor peptides I

1987-09-30

1988-10-18

Brown, J. R.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

8 to 10 amino acid residues in defined sequence

435 70, C07K 706

Patent

active

047788780

ABSTRACT:
An octapeptide inhibitor of myristoylating enzymes is disclosed having an amino acid sequence as follows or a physiologically acceptable amide or salt derivative thereof: ##STR1##

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Henderson et al., Proc. Natl. Acad. Sci. USA 80, 339-343 (1983).
Cross et al., Molec. Cell. Biol. 4, 1834-42 (1984).
Kamps et al., Proc. Natl. Acad. Sci. USA 82, 4625-28 (1985).
Towler & Glaser, Biochemistry 25, 878-84 (1986).
Towler & Glaser, Proc. Natl. Acad. Sci., USA 83, 2812-16 (1986).
Towler et al., Proc. Natl. Acad. Sci. USA 84, 2708-2712 (1987).

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