Novel heterocyclic esters of benzopyranopyridines

Details Novel heterocyclic esters of benzopyranopyridines Novel heterocyclic esters of benzopyranopyridines

1976-03-08

1977-08-16

Randolph, John D.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424267, 26029358, C07D49104

Patent

active

040426947

ABSTRACT:
Novel heterocyclic esters of benzopyranopyridines represented by the formula ##STR1## wherein R.sub.1 is hydrogen, lower alkyl, lower alkanoyl, cycloalkyl-lower alkyl, cycloalkyl-lower alkanoyl, lower alkenyl, lower alkynyl, halo-loweralkenyl, phenyl-lower alkyl, phenyl-lower alkenyl or phenyl-lower alkynyl; R.sub.2 is lower alkyl; R.sub.3 is an alkyl having one to twenty carbon atoms or a cycloalkyl-lower alkyl, Y is a straight or branched chain alkylene having one to eight carbon atoms, and R.sub.4 is a group of the formula ##STR2## a is an integer from 1 to 4, b is an integer from 1 to 4 and X is CH.sub.2, O, S or N--R.sub.5 with R.sub.5 being hydrogen or lower alkyl, with the limitation that when X is O, S or N--R.sub.5, a and b each must be 2 and R.sub.6 is hydrogen or a lower alkyl group bonded to a carbon in the ring; and the acid addition salts thereof.

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patent: 3522260 (1970-07-01), Shulgin
patent: 3542789 (1970-11-01), Satzinger
patent: 3656906 (1972-04-01), Bullock
patent: 3728360 (1973-04-01), Pars et al.
patent: 3787424 (1974-01-01), Pars et al.
patent: 3991194 (1976-11-01), Harris et al.
Buzas et al., Compt. Rend. 256, 1804-1806 (19639.

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