Novel heterocyclic dicarboxylic acids

Details Novel heterocyclic dicarboxylic acids Novel heterocyclic dicarboxylic acids

1990-09-10

1992-01-14

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546227, 546245, 549420, C07D21160, A61K 3144

Patent

active

050811355

ABSTRACT:
A compound selected from the group consisting of a compound of the formula ##STR1## wherein the dotted lines represent a possible endo or exo double bond, R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen, alkyl of 1 to 8 carbon atoms, alkenyl and alkynyl of 2 to 8 carbon atoms, aryl of 6 to 14 carbon atoms, aralkyl of 7 to 18 carbon atoms and ##STR2## R'.sub.2 is alkyl of 1 to 8 carbon atoms or aryl of 6 to 14 carbon atoms, X is --O-- or --NR--, R is selected from the group consisting of hydrogen ##STR3## and --COOR', R' is hydrogen or alkyl of 1 to 8 carbon atoms, Y is selected from the group consisting of hydrogen, alkyl of 1 to 8 carbon atoms and alkenyl and alkynyl of 2 to 8 carbon atoms, all optionally substituted with at least one halogen or --OH, with the proviso that if Y is --OH, X is not --NH-- and their non-toxic, pharmaceutically acceptable addition salts of acids or bases having antibacterial and immunological properties.

REFERENCES:
Hilpert et al., "Total Synthesis of Betalaius", CA 102(23):203798p (1984).
Hermann et al., "Total Synthesis of Betalaius", CA 87(3):22981u (1977).

Affiliated with

Also associated with

Rating

Novel heterocyclic dicarboxylic acids does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Novel heterocyclic dicarboxylic acids, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel heterocyclic dicarboxylic acids will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-541889