Novel guanidinomethylcyclohexanecarboxylic acid compounds and an

Details Novel guanidinomethylcyclohexanecarboxylic acid compounds and an Novel guanidinomethylcyclohexanecarboxylic acid compounds and an

1986-03-06

1987-07-21

Mars, Howard T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514563, 514927, 560 34, 562439, A61K 31245, C07C12900

Patent

active

046818952

ABSTRACT:
Novel N-phenyl-trans-4-guanidinomethylcyclohexanecarboxamide compounds of the formula: ##STR1## wherein R is hydrogen atom or a lower alkyl group, or a pharmaceutically acceptable salt thereof, which have excellent anti-ulcer activities and hence are useful as an anti-ulcer drug, and a pharmaceutical composition useful for the treatment and prophylaxis of peptic ulcers which comprises as an active ingredient the compound as set forth above in admixture with a conventional pharmaceutically acceptable carrier or diluent.

REFERENCES:
patent: 4224342 (1980-09-01), Fujii et al.
Nippon Chemiphar Co. Ltd., C. A. 97:66400 g, Jpn. First Publicn. No. 75920/1982.
Nippon Chemphar Co. Ltd., C. A. 98: 178818; Jpn. First Publicn. No. 197256/1982.

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