Novel glycopeptide and methods of isolating and using the same

Details Novel glycopeptide and methods of isolating and using the same Novel glycopeptide and methods of isolating and using the same

1980-07-03

1983-05-10

Fagelson, Anna P.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424 9, 424 95, 424 99, 424103, 424177, 424180, 536 11, A61K 4900, C07C10352, C07G 700

Patent

active

043828876

ABSTRACT:
A novel glycopeptide is disclosed, which consists of a sugar moiety having a structural formula ##STR1## and a peptide moiety linking to the sugar moiety through N-glycoside bond. The glycopeptide is isolated from organs of normal animals, especially kidney, or urine from healthy human being, and has a biological activity of inducing lesions of kidney in animals. The lesions of kidney induced by an injection of the glycopeptide are very similar to spectrum of human glomerulonephritis. Accordingly, an experimental model for study on human glomerulonephritis is established.

REFERENCES:
Shibata, Biochim et Biophy. Acta, vol. 499, 1977 pp. 392-403.
Shibata, Chem. Abs., vol. 86, 1977 Ab. No. 86:53552p.
Shibata, The J. of Immunol. vol. 106, May 1971 p. 1284.
Shibata, The J. of Immunol. vol. 102, 1969 pp. 593-601.
Shibata, The J. of Immunol. vol. 104, 1970 pp. 215-223.
Shibata, Japan. J. Exp. Med. vol. 37, No. 4, 1967 pp. 337-353.
Shibata, Carbohydrate Res. vol. 81, 1980 pp. 345-348.
Shibata, Carbohydrate Res. vol. 86, 1980 pp. 316-320.
Spiro, The J. Biol. Chem., vol. 242, 1967 pp. 1923-1932.
Shibata, Japan Medical Res. Foundation Pub. vol. 7, (Glomerulonephritis) 1979 pp. 23-38.
Nagasawa, Supra p. 39.
Shibata, Nephron, vol. 16, 1976 pp. 241-255.

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