Novel enzyme derivatives

Details Novel enzyme derivatives Novel enzyme derivatives

1984-12-21

1986-07-15

Schain, Howard E.

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Hydrolases

424 85, 424 88, 424101, 435177, 435180, 435181, 435185, 435188, 435215, 435217, 436547, 514 2, 530363, 530380, 530387, C12N 996, C12N 1106

Patent

active

046005803

ABSTRACT:
A derivative of a fibrinolytic enzyme in which the catalytic site on the enzyme which is responsible for fibrinolytic activity is blocked by a human protein attached thereto by way of a reversible linking group.

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patent: 4134792 (1979-01-01), Boguslaski et al.
patent: 4232119 (1980-11-01), Carlsson et al.
patent: 4233401 (1980-11-01), Yoshida et al.
patent: 4275000 (1981-06-01), Ross
patent: 4285932 (1981-08-01), Smith
patent: 4305926 (1981-12-01), Everse et al.
patent: 4464468 (1984-08-01), Aurameas et al.
patent: 4507283 (1985-03-01), Smith
patent: 4536391 (1985-08-01), Miyazaki et al.
J. of Immunol. Methods, 35:267-275 (1980), Terouanne et al.

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