Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...
Patent
1977-10-20
1978-07-25
Phillips, Delbert R.
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Reduced antigenicity, reduced ability to bind complement, or...
260 8, 2601125R, A61K 3700, C08L 3700, C07C10352
Patent
active
041030052
ABSTRACT:
Two enkephalin analogs, [D-Met.sup.2, Thz.sup.5 ]-enkephalinamide and [D-Thr.sup.2, Thz.sup.5 ]-enkephalinamide have been found to be potent analgesic agents.
REFERENCES:
bajusz, et al., Febs. Letters 76, 91 (1977).
Felix, et al., Int. J. Pept. Proct. Res. 5, 201 (1973).
Rosamond, et al., J. Med. Chem. 19, 873 (1976).
Hambrook, et al., Nature (London), 262, 782 (1976).
Pert, et al., Science 194, 330 (1976).
Bajusz, et al., Acta Biochem. Biophys. Acad. Sci. Hung. II, 305 (1976).
Roemer, et al., Nature 268, 547 (1977).
Gould George M.
Hoffmann-La Roche Inc.
Phillips Delbert R.
Welt Samuel L.
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