Surgery – Respiratory method or device – Ozone or ion generation
Patent
1975-03-10
1976-04-06
Medbery, Aldrich F.
Surgery
Respiratory method or device
Ozone or ion generation
128268, 128270, 128272, 128285, 424 20, 128130, A61F 546, A61M 700, A61J 100
Patent
active
039482626
ABSTRACT:
A drug delivery device for administering a drug at a controlled rate for a prolonged period of time to produce a local or systemic physiological or pharmacological effect is comprised of a wall surrounding a reservoir containing a drug. The reservoir is formed of a drug carrier permeable to the passage of the drug and in which the drug has limited solubility. The wall is formed in at least a part of a drug release rate controlling material also permeable to the passage of the drug, but the rate of passage of the drug through the wall is lower than the rate passage of the drug through the drug carrier so that drug release by the wall is the drug release rate controlling step for releasing drug from the drug delivery device.
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patent: 3598115 (1971-08-01), Horne, Jr.
patent: 3705938 (1972-12-01), Hyman
patent: 3710795 (1973-01-01), Higuchi et al.
Kincl, et al., "Sustained Release Hormonal Preparations," Steroids, Vol. 11, No. 5, May 1968, pp. 673-680.
Chang, et al., "Sustained Release Hormonal Preparations," Fertility and Sterility, Vol. 21, No. 2, Feb. 1970, pp. 134-139.
Unknown, "An Unusually Effective IUD Device That Has `No Systemic Effects`", Medical World News, May 25, 1973, pp. 55-56.
Kratochvil, et al., "Sustained Release Hormonal Preparations," Steroids, Vol. 15, No. 4, Apr. 1970, pp. 505-511.
ALZA Corporation
Ciotti Thomas E.
Mandell Edward L.
Medbery Aldrich F.
Sabatine Paul L.
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