Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses
Patent
1985-04-25
1990-02-20
Wiseman, Thomas G.
Chemistry: molecular biology and microbiology
Treatment of micro-organisms or enzymes with electrical or...
Modification of viruses
435255, 435320, 435940, 435183, 935 28, 935 56, 935 69, 935 14, 935 64, C12N 1500, C12N 118, C12R 185
Patent
active
049026208
ABSTRACT:
The present invention is a novel method for maintaining and selecting recombinant DNA-containing host cells wherein the DNA encoding a selectable phenotype and the DNA encoding a useful polypeptide are the same. The aforementioned DNA is useful for expressing .delta.-aminolevulinic acid synthetase (ALAS) for the ultimate expression of .delta.-aminolevulinic acid (ALA) in yeast and related organisms. The invention further comprises plasmids pIT300, pIT301, pIT302, pIT304, pIT305, pIT306 and related Saccharomyces ALA deficient transformants. ALA is a five carbon amino acid that is useful as a light dependent herbicide.
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Bard Martin
Ingolia Thomas D.
Dahling Gerald V.
Eli Lilly and Company
Norman Douglas K.
Peet Richard C.
Whitaker Leroy
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