Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1987-03-20
1989-11-07
Berch, Mark L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
540551, C07D41704, A61K 31555
Patent
active
048792888
ABSTRACT:
11-[4-[2-(2-Hydroxyethoxy)ethyl]-1-piperazinyl]dibenzo[b,f][1,4 ]thiazepine is disclosed as a neuroleptic with a much reduced incidence of side effects such as acute dystonia and dyskinesia and tardive diskinesia.
REFERENCES:
patent: 3325497 (1967-06-01), Fouche
patent: 3389139 (1968-06-01), Schmutz et al.
patent: 3459745 (1969-08-01), Fouche
patent: 3539573 (1970-11-01), Schmutz et al.
patent: 3723466 (1973-03-01), Malon
patent: 3755340 (1973-08-01), Hoehn et al.
patent: 3761481 (1973-09-01), Nakanishi
patent: 3928356 (1975-12-01), Umio et al.
patent: 3962248 (1976-06-01), Schneider
patent: 4096261 (1978-06-01), Horrom et al.
patent: 4097597 (1978-06-01), Horrom et al.
patent: 4308207 (1981-12-01), Hunziker et al.
Chemical Abstracts, vol. 93, No. 11, 15th Sep. 1980, p. 727, col. 1, abstract No. 114451y, Columbus, OH, US; abstract of: "Piperazinyldibenzazepine", RES. DISCL. 1980, 192, 158-159.
"Piperazinyldibenzazepine", RES. DISCL. 1980, 192, 158-159.
Tobler, E. and Foster, D. J. Helv. Chim. Acta., 48:336 (1965).
Ther, L. and Schramm, H. Arch. Int. Pharmacodyn., 138:302 (1962).
Puech, A. J., Simon, P. and Boissier, J., Eur. J. Pharm., 50:291 (1978).
Swerdlow, U. R. and Koob, G. F., Pharmacol. Biochem. and Behav., 23:303 (1985).
Carlson, A. and Lindquist, M., Acta. Pharmac. Tox., (1963) 20:140.
Saller, L. F. and Salama, A. I., J. Chromatography, (1984) 309:287.
Herz, A., Int. Rev. Neurobiol., (1960) 2:229-277.
Barany, S., Haggstrom, J. H. and Gunne, L. M., Acta. Pharmacol. et. Toxicol., (1983) 52:86.
Liebman, J. and Neale, R., Psychopharmacology (1980), 68:25-29.
Weiss, B. and Santelli, S., Science, (1978), 200:799-801.
Gunne, A. and Barany, S., Psychopharmacology, (1979), 63:195-198.
Migler Bernard M.
Warawa Edward J.
Berch Mark L.
ICI Americas Inc.
Jackson Thomas E.
Jones James T.
Miano Rosemary M.
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