Novel dibenzo[a,g]quinolizinium compounds

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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260287D, 260287C, 424258, C07D21510

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active

040425924

ABSTRACT:
9-Hydroxydibenzo[a,g]quinolizinium compound of the formula: ##STR1## wherein R.sub.5, R.sub.6, R.sub.8 and R.sub.13 are each hydrogen or lower alkyl, and X.sup.- is a pharmaceutically acceptable anion. Additional substituent may be present on ring A and D. Betaines and 9-acylates are also provided. They inhibit growth of transplanted sarcoma or leukemia strains into mice.

REFERENCES:
patent: 3341544 (1967-09-01), Melzer et al.
patent: 3483206 (1969-12-01), Weiner
patent: 3565899 (1971-02-01), Doebel et al.
patent: 3920665 (1975-11-01), Shimada et al.
Tet. Let. No. 11 pp. 803-806 (1973).

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