Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1975-05-01
1977-08-16
Phillips, Delbert R.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
260287D, 260287C, 424258, C07D21510
Patent
active
040425924
ABSTRACT:
9-Hydroxydibenzo[a,g]quinolizinium compound of the formula: ##STR1## wherein R.sub.5, R.sub.6, R.sub.8 and R.sub.13 are each hydrogen or lower alkyl, and X.sup.- is a pharmaceutically acceptable anion. Additional substituent may be present on ring A and D. Betaines and 9-acylates are also provided. They inhibit growth of transplanted sarcoma or leukemia strains into mice.
REFERENCES:
patent: 3341544 (1967-09-01), Melzer et al.
patent: 3483206 (1969-12-01), Weiner
patent: 3565899 (1971-02-01), Doebel et al.
patent: 3920665 (1975-11-01), Shimada et al.
Tet. Let. No. 11 pp. 803-806 (1973).
Kanebo Ltd.
Phillips Delbert R.
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