Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific... – Synthetic or structurally-modified peptidoglycan or...
Patent
1980-08-07
1981-08-25
Jiles, Henry R.
Drug, bio-affecting and body treating compositions
Nonspecific immunoeffector, per se ; or nonspecific...
Synthetic or structurally-modified peptidoglycan or...
26034341, 435 76, 435119, 536 17R, 424181, A61K 31365, C07D49320, C07D31306
Patent
active
042859638
ABSTRACT:
There are disclosed certain new derivatives of C-076 compounds which have been isolated from the fermentation broth that produced the original C-076 compounds. The compounds retain the C-076 16-membered cyclic backbone, however, the groups attached thereto are considerably modified from the original C-076 compounds. The new compounds have been found to retain the biological activity of the parent C-076 compounds. The compounds are thus potent antiparasitic agents and compositions and methods for such uses are also disclosed.
REFERENCES:
patent: 3950360 (1976-04-01), Aoki et al.
patent: 4093629 (1978-06-01), Fisher
patent: 4171314 (1979-10-01), Chabala et al.
patent: 4173571 (1979-11-01), Chabala et al.
Arison Byron H.
Goegelman Robert T.
Gullo Vincent P.
Fan Jane T.
Jiles Henry R.
Merck & Co. , Inc.
Rose David L.
Westlake Harry E.
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