Novel derivatives of beta-endorphin, intermediates therefor and

Details Novel derivatives of beta-endorphin, intermediates therefor and Novel derivatives of beta-endorphin, intermediates therefor and

1977-06-16

1982-01-26

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Reduced antigenicity, reduced ability to bind complement, or...

2601125E, A61K 3700, C07C10352

Patent

active

043128572

ABSTRACT:
Novel hentriacontapeptides having the following amino acid sequence:

REFERENCES:
patent: 4038222 (1977-07-01), Li
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Ling et al., Chem. Abst., 86, 1977, p. 38887H.
Ling et al., Proc. Natl. Acad. Sci. USA, 73, 1976, pp. 3308-3310.
Guillemin et al., Biochimie, 1976, pp. 783-785.
Bradbury et al., Nature, 260, 1976, pp. 793-795.
Li et al., Proc. Natl. Acad. Sci., USA, 73, 1976, pp. 1145-1148.
Coy et al., Biochem and Biophys. Res. Comm. 73, 1976, pp. 632-638.
Pert. et al., Opiates and Endogenous Opioid Peptides, 1976, pp. 79-86.
Plotnikoff et al., Life Science, 19, pp. 1283-1288, 1976.
Kosterlitz et al., Life Science, 17, pp. 91-96, 1975.
Pert et al., Science, 194, pp. 330-332, 1976.
Ling et al., Biochem and Biophys. Res. Comm., 74, 1977, pp. 248-255.
Marks et al., Biochem and Biophys. Res. Comm., 74, 1977, pp. 1552-1559.

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