Novel derivative of N-(3,4,5-trimethoxy cinnamoyl) piperazine, i

Details Novel derivative of N-(3,4,5-trimethoxy cinnamoyl) piperazine, i Novel derivative of N-(3,4,5-trimethoxy cinnamoyl) piperazine, i

1975-07-15

1977-04-05

Demers, Arthur P.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260268C, 424250, C07D40302

Patent

active

040161544

ABSTRACT:
A compound having the formula ##STR1## and its pharmacologically acceptable acid addition salts. The compound is prepared by condensing N-(3,4,5-trimethoxy cinnamoyl) piperazine with N-(2-pyrrolidinone) chloroacetamide. The compounds possess peripheral and coronary vasodilatatory properties and hypotensive and antihypertensive properties.

REFERENCES:
patent: 3634411 (1972-01-01), Fauran et al.
patent: 3798325 (1974-03-01), Schindler et al.
patent: 3806510 (1974-04-01), Parcell
patent: 3826833 (1974-07-01), Schindler et al.
patent: 3828046 (1974-08-01), Doerhoefer
patent: 3856958 (1974-12-01), Lee
Turbanti et al., Chimica Therapeutica, vol. II (1967), p. 354.

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