Novel daunomycin derivatives, their aglycones and the use thereo

Details Novel daunomycin derivatives, their aglycones and the use thereo Novel daunomycin derivatives, their aglycones and the use thereo

1978-05-01

1980-03-04

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated via claimed linking group, bond, chelating agent,...

536 17R, 536 17A, 536 18, 260592, A61K 3171, C07H 1524

Patent

active

041917553

ABSTRACT:
Daunomycin derivatives of the formula: ##STR1## wherein R.sub.1 is a lower alkyl having from 1 to 4 carbon atoms and R is hydrogen or a trifluoroacetyl group are useful in treating certain mammalian tumors.

REFERENCES:
patent: 4025623 (1977-05-01), Arcamone et al.
patent: 4039663 (1977-08-01), Arcamone et al.
patent: 4067969 (1978-01-01), Penco et al.

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