Novel D-homo steroids

Details Novel D-homo steroids Novel D-homo steroids

1975-09-02

1977-05-24

Schwartz, Gerald A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260488B, 424311, 424331, C07C 4948

Patent

active

040255638

ABSTRACT:
D-homo steroids of the formula ##STR1## wherein X is H, F or CH.sub.3 ; Y is H, F or Cl; Z is CH.sub.2, CO, .beta.-HOCH.sub.2, .beta.-AcOCH.sub.2 or, when Y is Cl, also .beta.-FCH.sub.2 or .beta.-ClCH.sub.2 ; R.sub.1 is H or CH.sub.3, R.sub.2 is H, OH or AcO; and one of R.sub.3 and R.sub.4 is H and the other is OH or alkoxy or both are O, possess anti-inflammatory activity.

REFERENCES:
patent: 2860158 (1958-11-01), Clinton

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