Novel cyclopropylmethylamine derivatives

Details Novel cyclopropylmethylamine derivatives Novel cyclopropylmethylamine derivatives

1975-11-26

1978-07-25

Meyers, Albert T.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

2605705CA, A01N 920, A01N 924, C07C 9116, C07C 9128

Patent

active

041030303

ABSTRACT:
Novel cyclopropylmethylamine compounds of the formula: ##STR1## wherein Ar.sup.1 represents a phenyl group having one or more substituents selected from the group consisting of halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy and trifluoromethyl, of which at least one is present at the o- or m-position, Ar.sup.2 represents an unsubstituted phenyl group or a phenyl group substituted with one or more substituents selected from the group consisting of halogen and C.sub.1 -C.sub.4 alkyl, R represents hydrogen, C.sub.1 -C.sub.4 alkyl or C.sub.2 -C.sub.4 hydroxyalkyl and R' represents C.sub.1 -C.sub.4 alkyl or C.sub.2 -C.sub.4 hydroxyalkyl, and their non-toxic salts, which possess various useful pharmacological activities and can be produced by reduction of the corresponding compounds of the formula: ##STR2## wherein Ar.sup.1, Ar.sup.2, R and R' are each as defined above or by condensation of the corresponding compounds of the formula: ##STR3## wherein Ar.sup.1 and Ar.sup.2 are each as defined above and X is a conventional leaving (removable) group with amines of the formula: ##STR4## wherein R and R' are each as defined above.

REFERENCES:
patent: 3941833 (1976-03-01), Gognaco
J. Org. Chem. U.S.S.R.-5p178 (1969), Bolesov et al., New Rearrangement of 2,2'-(cyclopropylimino)diethanols.
Chem. Abst., 68(1) 243 (1968) - Teotino et al.

Affiliated with

Also associated with

Rating

Novel cyclopropylmethylamine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Novel cyclopropylmethylamine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel cyclopropylmethylamine derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1421908