Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1990-06-27
1992-02-11
Reamer, James H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
504104, A61K 31155
Patent
active
050876406
ABSTRACT:
Compounds of the formula: ##STR1## wherein R.sup.1 and R.sup.2 are independently fluorine, chlorine or bromine atom, and R.sup.3 is a C.sub.4 -C.sub.7 alkyl having at least a branch at the C.sub.1 position, exhibit K.sup.+ channel opening activity and are useful as hypotensive agents and coronary vasodilators.
REFERENCES:
patent: 4639268 (1987-01-01), Arotin et al.
patent: 4804780 (1989-02-01), Speltz et al.
patent: 5011837 (1991-04-01), Atwal et al.
Goto Katsumi
Morita Tominori
Nishimura Noriyasu
Sukamoto Takayuki
Yoshiizumi Kazuya
Kanebo Ltd.
Reamer James H.
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