Novel competitive assay for theophylline and reagent for use the

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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436537, 436544, 436545, 436546, 436801, 436805, 436808, 436815, 530807, 544267, 544268, 544271, 544272, 544273, G01N 3353

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048552267

ABSTRACT:
A novel competitive assay for theophylline wherein caffeine-like (7-substituted) labeled conjugates are used to detect the presence and/or amount of theophylline present in a test sample. The use of such conjugates in a competitive assay for theophylline results in improved sensitivity of the assay method. Where the assay method is a nephelometric or turbidimetric inhibition immunoassay procedure, the assay was found to be less temperature dependent than prior art immunoassays.

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