Novel class of acyl-derivatives of carnitine, process for prepar

Details Novel class of acyl-derivatives of carnitine, process for prepar Novel class of acyl-derivatives of carnitine, process for prepar

1988-05-31

1989-08-22

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514446, 514448, 549 64, 549 65, 549 71, 549 72, C07D33322, C07D33332

Patent

active

048596981

ABSTRACT:
A novel class of acyl-derivatives of carnitine is disclosed wherein the acyl radical is either the radical of unsaturated organic acids (typically, acrylic acid) or the radical of saturated organic acids substituted with tert-alkyl, cycloalkyl, cycloalkenyl, alkoxyl, heterocyclic and carboalkoxylradicals, or with aldehyde or hydroxy groups. These acyl-derivatives of carnitine are useful therapeutical agents in the treatment of cardiac disorders, hyperlipidaemias and hyperlipoproteinaemias.

REFERENCES:
patent: 4599350 (1986-07-01), Gayer et al.
patent: 4668800 (1987-05-01), Meyer et al.
patent: 4707491 (1987-11-01), Covey et al.

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