Novel chromogenic thrombin substrates

Details Novel chromogenic thrombin substrates Novel chromogenic thrombin substrates

1976-06-17

1977-12-06

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

1951035R, 195 99, C07C10352

Patent

active

040616258

ABSTRACT:
Substrate with high specificity to thrombin and thrombin-like enzymes having the formula: ##STR1## and salts thereof, wherein R.sub.1 is H or OH; R.sub.2 is nitrophenyl; and n is 1, 2 or 3 provided along with the method of use.

REFERENCES:
patent: 3388113 (1968-06-01), Guttmann et al.
patent: 3778426 (1973-12-01), Naffar
patent: 3867364 (1975-02-01), Umezawa et al.
patent: 3884896 (1975-05-01), Blomback et al.
patent: 3886136 (1975-05-01), Claeson et al.

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