Novel choline derivative and method for detemining serum choline

Details Novel choline derivative and method for detemining serum choline Novel choline derivative and method for detemining serum choline

1989-02-15

1991-01-08

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

435 20, C07C 976, C12Q 146

Patent

active

049837567

ABSTRACT:
A novel compound, 6-acetoxymethyl-2-naphthoylcholine halide, is very stable to nonenzymatic hydrolysis and react specifically with cholinesterase in serum. A UV method for determining cholinesterase activity in serum which uses the novel compound as a substrate permits very accurate and highly reproducible determination of cholinesterase activity in serum, and therefor is very useful for clinical examination.

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